Notes

A concurrent CBC/Diff should be drawn with this assay or the results of a concurrent CBC/Diff should be sent so that absolute cell values can be reported.

This test is New York DOH approved.

Collect

1 mL blood in EDTA (Lavender)

Minimum Collection Volume

1 mL in EDTA (Lavender)

Acceptable Specimen Collect Alternatives

1 mL in Sodium Heparin (Dark Green) or ACD-A (Pale Yellow)

Unacceptable Conditions

Frozen, clotted, hemolyzed or centrifuged specimens. Specimen collected in an unacceptable anticoagulant.

Storage/Transport Temperature

AMBIENT

Specimen Preparation

Transport whole blood at room temperature. Do not refrigerate or freeze.

Stability (from collection to initiation)

Ambient: 24 hours / Frozen: Unacceptable / Refrigerated: Unacceptable.

Performed

Mon-Fri (Specimen must be in the CBDI lab by 1700 on Fridays)

Performing Lab

CBDI DIL 513-636-4685

Methodology

Flow Cytometry

Reported

2 Days

Tests Included

Immunophenotyping of lymphocytes is performed and results are scored on a 0-4 scale based on different characterization for typical diagnosis, result interpretation is also included

Synonyms

  • Autoimmune Lymphoproliferative Panel
  • ALPS panel
  • ALPS score

Interpretive Data

This flow cytometry assay is intended to be used as a screening test.  Screening tests are not 100% sensitive nor specific, and a normal result should not preclude molecular sequencing if a patient’s clinical presentation suggests that the probability of a diagnosis is high.

CPT Codes

88184, 88185x10, 88188

Acceptable Specimen Collect Alternatives

1 mL in Sodium Heparin (Dark Green) or ACD-A (Pale Yellow)
Collection

Notes

A concurrent CBC/Diff should be drawn with this assay or the results of a concurrent CBC/Diff should be sent so that absolute cell values can be reported.

This test is New York DOH approved.

Collect

1 mL blood in EDTA (Lavender)

Minimum Collection Volume

1 mL in EDTA (Lavender)

Acceptable Specimen Collect Alternatives

1 mL in Sodium Heparin (Dark Green) or ACD-A (Pale Yellow)

Unacceptable Conditions

Frozen, clotted, hemolyzed or centrifuged specimens. Specimen collected in an unacceptable anticoagulant.

Storage/Transport Temperature

AMBIENT

Specimen Preparation

Transport whole blood at room temperature. Do not refrigerate or freeze.

Stability (from collection to initiation)

Ambient: 24 hours / Frozen: Unacceptable / Refrigerated: Unacceptable.

Performed

Mon-Fri (Specimen must be in the CBDI lab by 1700 on Fridays)

Performing Lab

CBDI DIL 513-636-4685
Ordering

Methodology

Flow Cytometry

Reported

2 Days

Tests Included

Immunophenotyping of lymphocytes is performed and results are scored on a 0-4 scale based on different characterization for typical diagnosis, result interpretation is also included

Synonyms

  • Autoimmune Lymphoproliferative Panel
  • ALPS panel
  • ALPS score
Result Interpretation

Interpretive Data

This flow cytometry assay is intended to be used as a screening test.  Screening tests are not 100% sensitive nor specific, and a normal result should not preclude molecular sequencing if a patient’s clinical presentation suggests that the probability of a diagnosis is high.
Laboratory Personnel Use

CPT Codes

88184, 88185x10, 88188

Acceptable Specimen Collect Alternatives

1 mL in Sodium Heparin (Dark Green) or ACD-A (Pale Yellow)